AustralieFrV1, Main, Exploration, bibRecord, 004076

Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Myeloma

Identifieur interne : 004076 ( Main/Exploration ); précédent : 004075; suivant : 004077

Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Myeloma

Auteurs : Lotfi Benboubker [France] ; Meletios A. Dimopoulos [Grèce] ; Angela Dispenzieri [États-Unis] ; John Catalano [Australie] ; Andrew R. Belch [Canada] ; Michele Cavo [Italie] ; Antonello Pinto [Italie] ; Katja Weisel [Allemagne] ; Heinz Ludwig [Australie] ; Nizar Bahlis [Canada] ; Anne Banos [France] ; Mourad Tiab [France] ; Michel Delforge [Belgique] ; Jamie Cavenagh [Royaume-Uni] ; Catarina Geraldes [Portugal] ; Je-Jung Lee [Corée du Sud] ; Christine Chen [Canada] ; Albert Oriol [Espagne] ; Javier De La Rubia [Espagne] ; LUGUI QIU ; Darrell J. White [Canada] ; Daniel Binder ; Kenneth Anderson ; Jean-Paul Fermand [France] ; Philippe Moreau [France] ; Michel Attal [France] ; Robert Knight ; GUANG CHEN ; Jason Van Oostendorp ; Christian Jacques ; Annette Ervin-Haynes ; Hervé Avet-Loiseau [France] ; Cyrille Hulin [France] ; Thierry Facon [France]

Source :

The New England journal of medicine [ 0028-4793 ] ; 2014.

RBID : Pascal:15-0024405

Descripteurs français

Pascal (Inist)
- Myélome, Lénalidomide, Dexaméthasone, Médecine, Homme, Anticancéreux, Immunomodulateur, Antiinflammatoire.
Wicri :
- topic : Médecine, Homme.

English descriptors

KwdEn :
- Antiinflammatory agent, Antineoplastic agent, Dexamethasone, Human, Immunomodulator, Lenalidomide, Medicine, Myeloma.

Abstract

BACKGROUND The combination melphalan-prednisone-thalidomide (MPT) is considered a standard therapy for patients with myeloma who are ineligible for stem-cell transplantation. However, emerging data on the use of lenalidomide and low-dose dexamethasone warrant a prospective comparison of the two approaches. METHODS We randomly assigned 1623 patients to lenalidomide and dexamethasone in 28-day cycles until disease progression (535 patients), to the same combination for 72 weeks (18 cycles; 541 patients), or to MPT for 72 weeks (547 patients). The primary end point was progression-free survival with continuous lenalidomide-dexamethasone versus MPT. RESULTS The median progression-free survival was 25.5 months with continuous lenalidomide-dexamethasone, 20.7 months with 18 cycles of lenalidomide-dexamethasone, and 21.2 months with MPT (hazard ratio for the risk of progression or death, 0.72 for continuous lenalidomide-dexamethasone vs. MPT and 0.70 for continuous lenalidomide-dexamethasone vs. 18 cycles of lenalidomide-dexamethasone; P<0.001 for both comparisons). Continuous lenalidomide-dexamethasone was superior to MPT for all secondary efficacy end points, including overall survival (at the interim analysis).

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Belch, Andrew R" sort="Belch, Andrew R" uniqKey="Belch A" first="Andrew R." last="Belch">Andrew R. Belch</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>University of Alberta and Cross Cancer Institute</s1>
<s2>Edmonton, AB</s2>
<s3>CAN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>University of Alberta and Cross Cancer Institute</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cavo, Michele" sort="Cavo, Michele" uniqKey="Cavo M" first="Michele" last="Cavo">Michele Cavo</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Seràgnoli Institute of Hematology, Bologna University School of Medicine</s1>
<s2>Bologna</s2>
<s3>ITA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Bologna</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pinto, Antonello" sort="Pinto, Antonello" uniqKey="Pinto A" first="Antonello" last="Pinto">Antonello Pinto</name>
<affiliation wicri:level="1"><inist:fA14 i1="17"><s1>L'Unità Operativa Complessa Ematologia Oncologica, Istituto Nazionale dei Tumori Fondazione G. Pascale, Istituto di Ricovero e Cura a Carattere Scientifico</s1>
<s2>Naples</s2>
<s3>ITA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<wicri:noRegion>Naples</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Weisel, Katja" sort="Weisel, Katja" uniqKey="Weisel K" first="Katja" last="Weisel">Katja Weisel</name>
<affiliation wicri:level="3"><inist:fA14 i1="18"><s1>University of Tübingen</s1>
<s2>Tübingen</s2>
<s3>DEU</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Tübingen</region>
<settlement type="city">Tübingen</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ludwig, Heinz" sort="Ludwig, Heinz" uniqKey="Ludwig H" first="Heinz" last="Ludwig">Heinz Ludwig</name>
<affiliation wicri:level="3"><inist:fA14 i1="19"><s1>First Department of Internal Medicine, Center for Oncology and Hematology, Wilhelminenspital</s1>
<s2>Vienna</s2>
<s3>AUS</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bahlis, Nizar" sort="Bahlis, Nizar" uniqKey="Bahlis N" first="Nizar" last="Bahlis">Nizar Bahlis</name>
<affiliation wicri:level="4"><inist:fA14 i1="13"><s1>University of Calgary</s1>
<s2>Calgary, AB</s2>
<s3>CAN</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Calgary</settlement>
<region type="state">Alberta</region>
</placeName>
<orgName type="university">Université de Calgary</orgName>
</affiliation>
</author>
<author><name sortKey="Banos, Anne" sort="Banos, Anne" uniqKey="Banos A" first="Anne" last="Banos">Anne Banos</name>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Centre Hospitalier de la Côte Basque</s1>
<s2>Bayonne</s2>
<s3>FRA</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bayonne</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tiab, Mourad" sort="Tiab, Mourad" uniqKey="Tiab M" first="Mourad" last="Tiab">Mourad Tiab</name>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Médecine Interne, Centre Hospitalier Départemental les Oudairies</s1>
<s2>La Roche-sur-Yon</s2>
<s3>FRA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">La Roche-sur-Yon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Delforge, Michel" sort="Delforge, Michel" uniqKey="Delforge M" first="Michel" last="Delforge">Michel Delforge</name>
<affiliation wicri:level="1"><inist:fA14 i1="20"><s1>University Hospital Leuven</s1>
<s2>Leuven</s2>
<s3>BEL</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Belgique</country>
<wicri:noRegion>University Hospital Leuven</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cavenagh, Jamie" sort="Cavenagh, Jamie" uniqKey="Cavenagh J" first="Jamie" last="Cavenagh">Jamie Cavenagh</name>
<affiliation wicri:level="3"><inist:fA14 i1="21"><s1>Department of Haematology, St. Bartholomew's Hospital, Barts Health NHS Trust</s1>
<s2>London</s2>
<s3>GBR</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Royaume-Uni</country>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Geraldes, Catarina" sort="Geraldes, Catarina" uniqKey="Geraldes C" first="Catarina" last="Geraldes">Catarina Geraldes</name>
<affiliation wicri:level="1"><inist:fA14 i1="22"><s1>Clinical Hematology Department, Coimbra University Hospitals</s1>
<s2>Coimbra</s2>
<s3>PRT</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Portugal</country>
<wicri:noRegion>Coimbra</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lee, Je Jung" sort="Lee, Je Jung" uniqKey="Lee J" first="Je-Jung" last="Lee">Je-Jung Lee</name>
<affiliation wicri:level="1"><inist:fA14 i1="23"><s1>Department of Hematology and Oncology, Chonnam National University Hwasun Hospital</s1>
<s2>Hwasun, Jeollanamdo</s2>
<s3>KOR</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Corée du Sud</country>
<wicri:noRegion>Hwasun, Jeollanamdo</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Christine" sort="Chen, Christine" uniqKey="Chen C" first="Christine" last="Chen">Christine Chen</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Toronto</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oriol, Albert" sort="Oriol, Albert" uniqKey="Oriol A" first="Albert" last="Oriol">Albert Oriol</name>
<affiliation wicri:level="3"><inist:fA14 i1="24"><s1>Clinical Hematology Department, Institut Català d'Oncologia-Hospital Germans Trias i Pujol, Institut Josep Carreras</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De La Rubia, Javier" sort="De La Rubia, Javier" uniqKey="De La Rubia J" first="Javier" last="De La Rubia">Javier De La Rubia</name>
<affiliation wicri:level="1"><inist:fA14 i1="25"><s1>Hospital Universitario La Fe and Universidad Católica de Valencia San Vicente Mártir</s1>
<s2>Valencia</s2>
<s3>ESP</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>Espagne</country>
<wicri:noRegion>Hospital Universitario La Fe and Universidad Católica de Valencia San Vicente Mártir</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lugui Qiu" sort="Lugui Qiu" uniqKey="Lugui Qiu" last="Lugui Qiu">LUGUI QIU</name>
</author>
<author><name sortKey="White, Darrell J" sort="White, Darrell J" uniqKey="White D" first="Darrell J." last="White">Darrell J. White</name>
<affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Dalhousie University and Queen Elizabeth II Health Sciences Centre</s1>
<s2>Halifax, NS</s2>
<s3>CAN</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Dalhousie University and Queen Elizabeth II Health Sciences Centre</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Binder, Daniel" sort="Binder, Daniel" uniqKey="Binder D" first="Daniel" last="Binder">Daniel Binder</name>
</author>
<author><name sortKey="Anderson, Kenneth" sort="Anderson, Kenneth" uniqKey="Anderson K" first="Kenneth" last="Anderson">Kenneth Anderson</name>
</author>
<author><name sortKey="Fermand, Jean Paul" sort="Fermand, Jean Paul" uniqKey="Fermand J" first="Jean-Paul" last="Fermand">Jean-Paul Fermand</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Hôpital Saint-Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>24 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moreau, Philippe" sort="Moreau, Philippe" uniqKey="Moreau P" first="Philippe" last="Moreau">Philippe Moreau</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Service d'Hématologie, Centre Hospitalier Universitaire (CHU)</s1>
<s2>Nantes</s2>
<s3>FRA</s3>
<sZ>25 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Attal, Michel" sort="Attal, Michel" uniqKey="Attal M" first="Michel" last="Attal">Michel Attal</name>
<affiliation wicri:level="3"><inist:fA14 i1="06"><s1>CHRU Hôpital Purpan</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>26 aut.</sZ>
<sZ>32 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Knight, Robert" sort="Knight, Robert" uniqKey="Knight R" first="Robert" last="Knight">Robert Knight</name>
</author>
<author><name sortKey="Guang Chen" sort="Guang Chen" uniqKey="Guang Chen" last="Guang Chen">GUANG CHEN</name>
</author>
<author><name sortKey="Van Oostendorp, Jason" sort="Van Oostendorp, Jason" uniqKey="Van Oostendorp J" first="Jason" last="Van Oostendorp">Jason Van Oostendorp</name>
</author>
<author><name sortKey="Jacques, Christian" sort="Jacques, Christian" uniqKey="Jacques C" first="Christian" last="Jacques">Christian Jacques</name>
</author>
<author><name sortKey="Ervin Haynes, Annette" sort="Ervin Haynes, Annette" uniqKey="Ervin Haynes A" first="Annette" last="Ervin-Haynes">Annette Ervin-Haynes</name>
</author>
<author><name sortKey="Avet Loiseau, Herve" sort="Avet Loiseau, Herve" uniqKey="Avet Loiseau H" first="Hervé" last="Avet-Loiseau">Hervé Avet-Loiseau</name>
<affiliation wicri:level="3"><inist:fA14 i1="06"><s1>CHRU Hôpital Purpan</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>26 aut.</sZ>
<sZ>32 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Occitanie (région administrative)</region>
<region type="old region">Midi-Pyrénées</region>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hulin, Cyrille" sort="Hulin, Cyrille" uniqKey="Hulin C" first="Cyrille" last="Hulin">Cyrille Hulin</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Hématologie, CHU Nancy-Brabois</s1>
<s2>Vandœuvre</s2>
<s3>FRA</s3>
<sZ>33 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Vandœuvre</wicri:noRegion>
<wicri:noRegion>CHU Nancy-Brabois</wicri:noRegion>
<wicri:noRegion>Vandœuvre</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Facon, Thierry" sort="Facon, Thierry" uniqKey="Facon T" first="Thierry" last="Facon">Thierry Facon</name>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Service des Maladies du Sang, Hôpital Claude Huriez, CHRU</s1>
<s2>Lille</s2>
<s3>FRA</s3>
<sZ>34 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The New England journal of medicine</title>
<title level="j" type="abbreviated">N. Engl. j. med.</title>
<idno type="ISSN">0028-4793</idno>
<imprint><date when="2014">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The New England journal of medicine</title>
<title level="j" type="abbreviated">N. Engl. j. med.</title>
<idno type="ISSN">0028-4793</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiinflammatory agent</term>
<term>Antineoplastic agent</term>
<term>Dexamethasone</term>
<term>Human</term>
<term>Immunomodulator</term>
<term>Lenalidomide</term>
<term>Medicine</term>
<term>Myeloma</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Myélome</term>
<term>Lénalidomide</term>
<term>Dexaméthasone</term>
<term>Médecine</term>
<term>Homme</term>
<term>Anticancéreux</term>
<term>Immunomodulateur</term>
<term>Antiinflammatoire</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Médecine</term>
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">BACKGROUND The combination melphalan-prednisone-thalidomide (MPT) is considered a standard therapy for patients with myeloma who are ineligible for stem-cell transplantation. However, emerging data on the use of lenalidomide and low-dose dexamethasone warrant a prospective comparison of the two approaches. METHODS We randomly assigned 1623 patients to lenalidomide and dexamethasone in 28-day cycles until disease progression (535 patients), to the same combination for 72 weeks (18 cycles; 541 patients), or to MPT for 72 weeks (547 patients). The primary end point was progression-free survival with continuous lenalidomide-dexamethasone versus MPT. RESULTS The median progression-free survival was 25.5 months with continuous lenalidomide-dexamethasone, 20.7 months with 18 cycles of lenalidomide-dexamethasone, and 21.2 months with MPT (hazard ratio for the risk of progression or death, 0.72 for continuous lenalidomide-dexamethasone vs. MPT and 0.70 for continuous lenalidomide-dexamethasone vs. 18 cycles of lenalidomide-dexamethasone; P<0.001 for both comparisons). Continuous lenalidomide-dexamethasone was superior to MPT for all secondary efficacy end points, including overall survival (at the interim analysis).</div>
</front>
</TEI>
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<li>Australie</li>
<li>Belgique</li>
<li>Canada</li>
<li>Corée du Sud</li>
<li>Espagne</li>
<li>France</li>
<li>Grèce</li>
<li>Italie</li>
<li>Portugal</li>
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<li>Toulouse</li>
<li>Tours</li>
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<orgName><li>Université de Calgary</li>
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<tree><noCountry><name sortKey="Anderson, Kenneth" sort="Anderson, Kenneth" uniqKey="Anderson K" first="Kenneth" last="Anderson">Kenneth Anderson</name>
<name sortKey="Binder, Daniel" sort="Binder, Daniel" uniqKey="Binder D" first="Daniel" last="Binder">Daniel Binder</name>
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<name sortKey="Guang Chen" sort="Guang Chen" uniqKey="Guang Chen" last="Guang Chen">GUANG CHEN</name>
<name sortKey="Jacques, Christian" sort="Jacques, Christian" uniqKey="Jacques C" first="Christian" last="Jacques">Christian Jacques</name>
<name sortKey="Knight, Robert" sort="Knight, Robert" uniqKey="Knight R" first="Robert" last="Knight">Robert Knight</name>
<name sortKey="Lugui Qiu" sort="Lugui Qiu" uniqKey="Lugui Qiu" last="Lugui Qiu">LUGUI QIU</name>
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<country name="Grèce"><region name="Attique (région)"><name sortKey="Dimopoulos, Meletios A" sort="Dimopoulos, Meletios A" uniqKey="Dimopoulos M" first="Meletios A." last="Dimopoulos">Meletios A. Dimopoulos</name>
</region>
</country>
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</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Catalano, John" sort="Catalano, John" uniqKey="Catalano J" first="John" last="Catalano">John Catalano</name>
</noRegion>
<name sortKey="Ludwig, Heinz" sort="Ludwig, Heinz" uniqKey="Ludwig H" first="Heinz" last="Ludwig">Heinz Ludwig</name>
</country>
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<name sortKey="White, Darrell J" sort="White, Darrell J" uniqKey="White D" first="Darrell J." last="White">Darrell J. White</name>
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<country name="Italie"><noRegion><name sortKey="Cavo, Michele" sort="Cavo, Michele" uniqKey="Cavo M" first="Michele" last="Cavo">Michele Cavo</name>
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<name sortKey="Pinto, Antonello" sort="Pinto, Antonello" uniqKey="Pinto A" first="Antonello" last="Pinto">Antonello Pinto</name>
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<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Weisel, Katja" sort="Weisel, Katja" uniqKey="Weisel K" first="Katja" last="Weisel">Katja Weisel</name>
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<country name="Belgique"><noRegion><name sortKey="Delforge, Michel" sort="Delforge, Michel" uniqKey="Delforge M" first="Michel" last="Delforge">Michel Delforge</name>
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</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Cavenagh, Jamie" sort="Cavenagh, Jamie" uniqKey="Cavenagh J" first="Jamie" last="Cavenagh">Jamie Cavenagh</name>
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<country name="Portugal"><noRegion><name sortKey="Geraldes, Catarina" sort="Geraldes, Catarina" uniqKey="Geraldes C" first="Catarina" last="Geraldes">Catarina Geraldes</name>
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   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
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   |type=    RBID
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   |texte=   Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Myeloma
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	Serveur d'exploration sur les relations entre la France et l'Australie
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Serveur d'exploration sur les relations entre la France et l'Australie

Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Myeloma

Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Myeloma

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